Semax is a synthetic heptapeptide with the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). This compound is structurally derived from adrenocorticotropic hormone (ACTH), specifically containing the ACTH(4-7) fragment with an added C-terminal Pro-Gly-Pro tripeptide that enhances its stability and blood-brain barrier penetration capabilities.
Research Applications
Semax has been extensively studied for its potential properties including:
Neuroprotective mechanisms in cerebral ischemia models
Enhancement of cognitive function parameters
Neurorestorative activity in research models
Modulation of neurotrophic factor expression
Effects on brain-derived neurotrophic factor (BDNF) levels
Influence on default mode network activity Wikipedia
The compound has been the subject of numerous research papers investigating its role in learning processes, memory formation, and neuroprotection. Laboratory studies have examined its influence on various neuronal signaling pathways and gene expression patterns.
Storage & Handling Recommendations
Extreme Peptide’s Semax 5mg is provided as a lyophilized powder for maximum stability. For optimal compound integrity:
Store unopened vials at -20°C in a laboratory-grade freezer
Protect from light, moisture, and repeated freeze-thaw cycles
Reconstitute in sterile water (recommended minimum concentration: 100 µg/ml) prospecbio
Reconstituted solutions should be stored at 4°C and used within 7 days
For long-term storage of reconstituted solutions, add a carrier protein (0.1% HSA or BSA)
Aliquot reconstituted solutions to minimize freeze-thaw cycles
Quality Assurance
Each batch of Extreme Peptide’s Semax undergoes:
Advanced HPLC analysis to verify >99% purity
Mass spectrometry confirmation of molecular identity
Endotoxin testing to ensure research compatibility
Sterile filtration and lyophilization under controlled conditions
Batch-specific Certificate of Analysis available upon request
Shipping & Handling
Temperature-controlled packaging to maintain product integrity
Fast delivery options available domestically and internationally
All products ship from our ISO-certified US laboratory facilities
Tracking information provided for all shipments
Guaranteed replacement for any shipments compromised during transit
Research Considerations
In laboratory settings, Semax has traditionally been administered via several routes including intranasal application in concentrations ranging from 0.1% to 1.0%. Peptides Researchers should determine appropriate protocols based on specific experimental designs.
Important Notice
This product is sold exclusively for laboratory research purposes. Not for human consumption or diagnostic applications. By purchasing this product, you confirm compliance with all applicable regulations regarding research compounds.
